Journal: Heliyon

Article Title: Performance and correlation of ten commercial immunoassays for the detection of SARS-CoV-2 antibodies

doi: 10.1016/j.heliyon.2022.e12614

Figure Lengend Snippet: Details of the evaluated ten commercial immunoassays.

Article Snippet: All assays showed moderate to high correlation with GenScript sVNT (r = 0.58 to r = 0.98), except Roche total antibodies (r = 0.48).

Techniques: Chemiluminescence Immunoassay, Enzyme-linked Immunosorbent Assay, Inhibition, Virus, Neutralization

Journal: Heliyon

Article Title: Performance and correlation of ten commercial immunoassays for the detection of SARS-CoV-2 antibodies

doi: 10.1016/j.heliyon.2022.e12614

Figure Lengend Snippet: The sensitivity and specificity of each commercial immunoassay.

Article Snippet: All assays showed moderate to high correlation with GenScript sVNT (r = 0.58 to r = 0.98), except Roche total antibodies (r = 0.48).

Techniques:

Journal: Heliyon

Article Title: Performance and correlation of ten commercial immunoassays for the detection of SARS-CoV-2 antibodies

doi: 10.1016/j.heliyon.2022.e12614

Figure Lengend Snippet: Lists of false positives, identified acute infecting pathogens, and results from all assays.

Article Snippet: All assays showed moderate to high correlation with GenScript sVNT (r = 0.58 to r = 0.98), except Roche total antibodies (r = 0.48).

Techniques:

Journal: Heliyon

Article Title: Performance and correlation of ten commercial immunoassays for the detection of SARS-CoV-2 antibodies

doi: 10.1016/j.heliyon.2022.e12614

Figure Lengend Snippet: Violin Plot of nine COVID-19 commercial immunoassays for detecting SARS-CoV-2 antibodies compared to GenScript sVNT. (A). Abbott IgG compared to GenScript sVNT. (B). FREND™ IgG compared to GenScript sVNT. (C). Roche total antibodies compared to GenScript sVNT. (D). Snibe IgG compared to GenScript sVNT. (E). Beckman IgG compared to GenScript sVNT. (F). Mindray IgG compared to GenScript sVNT. (G). Mindray total antibodies compared to GenScript sVNT. (H). Siemens total antibodies compared to GenScript sVNT. (I). Vazyme sVNT compared to GenScript sVNT.

Article Snippet: All assays showed moderate to high correlation with GenScript sVNT (r = 0.58 to r = 0.98), except Roche total antibodies (r = 0.48).

Techniques:

Journal: ACS Infectious Diseases

Article Title: Multiplexed Serum Antibody Screening Platform Using Virus Extracts from Endemic Coronaviridae and SARS-CoV-2

doi: 10.1021/acsinfecdis.0c00725

Figure Lengend Snippet: Comparison of the DigiWest seroconversion assay with commercially available SARS-CoV-2 assays. Concordance (Cohen’s κ) and correlation coefficients (Spearman’s r ) of DigiWest data and the commercially assays from Roche (a), Siemens (b), and Euroimmun IgG (c) were calculated and are shown below the plotted data; cutoff values are depicted as a black line in the scatter plot. For the Euroimmun IgG, two different κ values were calculated; when borderline results (as defined by the manufacturer) were considered positive, κ was 0.9180. If the borderline results were considered negative, the concordance for Euroimmun IgG was 0.8874. In (d), the correlation coefficients (Spearman’s r ) between all used assays are shown in a heat map. The highest value (Spearman’s r = 0.91) for DigiWest was found for the Roche system, and the lowest value (Spearman’s r = 0.78) for DigiWest vs Euroimmun IgA is shown of Spearman’s r values.

Article Snippet: The highest overall correlation was found between Siemens and Euroimmun IgG (Spearman’s r = 0.94; 95% CI; 0.93–0.96), and the lowest overall correlation was found between Euroimmun IgA and Roche (Spearman’s r = 0.73; 95% CI; 0.66–0.78).

Techniques: